Mendeley Brainstorm – Send in the Clones?

Twenty years ago, the first sheep was cloned; there have been huge advances since.
Twenty years ago, the first sheep was cloned from an adult cell; there have been huge advances since.

Twenty years ago, Dolly, the first sheep cloned from an adult cell, was revealed to the world. Since then, cloning and genetic manipulation technologies have advanced considerably. Should we welcome a new era of genetic science? Or is our knowledge growing faster than our wisdom? We are looking for the most well thought out answer to this question in up to 150 words: use the comment feature below the blog and please feel free to promote your research! The winner will receive an Amazon gift certificate worth £50 and a bag full of Mendeley items; competition closes April 12, 2017.

Hello, Dolly

On February 22, 1997, the Roslin Institute in Scotland announced the arrival of Dolly, the first mammal cloned from an adult cell. According to the Institute, “in the week following the announcement…(we) received 3,000 phone calls from around the world”. Dolly had captured the public’s imagination about the potential of cloning, which at one point had been thought to be impossible.

Spinoffs

Dr. Shinya Yamanaka, the 2012 winner of the Nobel Prize in Medicine was intellectually stimulated by Dolly’s arrival. He subsequently investigated how the adult DNA which had been used to create Dolly had been revivified. The eventual result was “induced pluripotent stem cells”, which “have become a scientific workhorse, providing limitless supplies of differentiated cells and tissue for use in the lab” (Economist, 2017). They also are “an invaluable tool for modelling human diseases and screening drugs” (Economist, 2017).\

Moral Objections

Cloning technologies have always been controversial. Many ethicists and public figures have questioned whether scientists have the right to “play God” and alter the building blocks of humanity. Some countries, including the United States, have implemented restrictions on this research.

Send in the Clones?

Are these concerns overblown? Or is our knowledge growing faster than our wisdom? What is the future of cloning in your view? Tell us!

Need Funding for Your Research?

Here are some of the latest funding opportunities for biology researchers provided by Mendeley Funding:

Organisation Opportunity
Oak Ridge Associated Universities Molecular biologist research opportunity in plant viruses
University of East Anglia Cloning and expression of topoisomerase genes from Trypanosoma brucei
Developing methods for genetically encoded unnatural amino acids to develop novel proteins
National Institutes of Health Cancer and stem cells epigenetics
Ancillary studies to the NIDDK intestinal stem cell consortium
Spermatogenic stem cell culture systems to preserve and restore reproductive capacity in males
Stem cell-derived blood products for therapeutic use: Technology improvement
John Templeton Foundation Genetics – Large grant
Genetics – Small grant

About Mendeley Brainstorms

Our Brainstorms are challenges so we can engage with you, our users, on the hottest topics in the world of research.  We look for the most in-depth and well thought through responses; the best response as judged by the Mendeley team will earn a prize.

References

Gene editing, clones and the science of making babies. (2017). The Economist. [online] Available at: http://www.economist.com/news/leaders/21717035-ways-reproducing-without-sexual-intercourse-are-multiplying-history-suggests-they-should [Accessed 23 Feb. 2017].

Hello, again, Dolly. (2017). The Economist. [online] Available at: http://www.economist.com/news/briefing/21717028-twenty-years-ago-world-met-first-adult-clone-sheep-called-dolly-her-legacy-lives [Accessed 23 Feb. 2017].

The Life of Dolly | Dolly the Sheep. (2017). [online] Dolly.roslin.ed.ac.uk. Available at: http://dolly.roslin.ed.ac.uk/facts/the-life-of-dolly/ [Accessed 23 Feb. 2017].

One thought on “Mendeley Brainstorm – Send in the Clones?

  1. The current EU standpoint is based on: “the scientific fact that currently, cloning causes significantly more animal suffering than conventional breeding.” (1*, 2*). However as such it can be argued that there is nothing wrong with cloning – to help animals to get rid of “weak” genetic structures. The phenomenon exist also in nature: The case of identical twins. If one take the case to the extreme, on the one hand the cloned animals might become treated as machines, products and humans might also treat in the end each other as machines, tools for trade. Here is no any sense. When totally banning cloning on the other hand, animals, humans might have disadvantages in case of serious genetic malfunctions causing illnesses from which it is challenging to recover. It can be stated that the approach of the EU is the right one. A complex multi-dimensional theme must be kept within a simple, clear framework.

    References:
    1* The European Commission (2017). “Cloning” , Last updated 16/3/2017. Available at: https://ec.europa.eu/food/animals/welfare/other_aspects/cloning_en
    2* Pete Wedderburn (2015). “No clones please, we’re European!” The Telegraph, 14 September 2015. Available at: http://www.telegraph.co.uk/pets/no-clones-please-were-european/

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